Marc Bigaud Selected Research

sphingosine 1-phosphate lyase (aldolase)

1/2013

Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis.

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Marc Bigaud Research Topics

Disease

5	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 08/2023 - 09/2012
5	Multiple Sclerosis 06/2023 - 04/2011
4	Inflammation (Inflammations) 01/2020 - 01/2013
3	Disease Progression 06/2023 - 01/2014
2	Atrophy 08/2023 - 11/2022
2	Demyelinating Diseases (Demyelinating Disease) 08/2023 - 01/2022
2	Lymphoma (Lymphomas) 12/2020 - 01/2020
2	Autoimmune Diseases (Autoimmune Disease) 12/2020 - 12/2019
2	Arthritis (Polyarthritis) 01/2020 - 01/2016
2	Necrosis 01/2016 - 03/2004
1	Chronic Progressive Multiple Sclerosis 08/2023
1	Severe Acute Respiratory Syndrome 06/2023
1	COVID-19 06/2023
1	Lymphopenia (Lymphocytopenia) 11/2022
1	Hypersensitivity (Allergy) 01/2022
1	Tertiary Lymphoid Structures 01/2022
1	Retinal Degeneration 01/2022
1	Optic Neuritis (Retrobulbar Neuritis) 01/2022
1	Neoplasms (Cancer) 01/2020
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2020
1	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 01/2020
1	Sialadenitis 01/2019
1	Pathologic Processes 01/2019
1	Hemorrhage 01/2016
1	Fibrosis (Cirrhosis) 01/2016
1	Edema (Dropsy) 01/2016
1	Neointima 02/2004

Drug/Important Bio-Agent (IBA)

5	Fingolimod Hydrochloride (FTY720)FDA Link 08/2023 - 04/2011
4	siponimodIBA 08/2023 - 01/2022
3	Sphingosine-1-Phosphate ReceptorsIBA 06/2023 - 04/2011
3	Peptide Hydrolases (Proteases)FDA Link 01/2020 - 12/2019
2	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 08/2023 - 04/2011
2	Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinIBA 12/2020 - 04/2015
2	AutoantibodiesIBA 01/2020 - 01/2019
2	NIBR-0213IBA 01/2016 - 09/2012
1	salicylhydroxamic acid (SHAM)IBA 11/2022
1	Retinaldehyde (Retinal)IBA 01/2022
1	ocrelizumabIBA 01/2022
1	ofatumumab FDA Link 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Antigen-Antibody Complex (Immune Complex)IBA 01/2020
1	Immunoglobulin E (IgE)IBA 01/2020
1	Inosine Triphosphate (ITP)IBA 01/2020
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	CytokinesIBA 01/2020
1	Therapeutic UsesIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2014
1	SphingolipidsIBA 01/2013
1	sphingosine 1-phosphate lyase (aldolase)IBA 01/2013
1	DiureticsIBA 03/2004
1	Vasoconstrictor AgentsIBA 02/2004

Therapy/Procedure

1	Critical Care (Surgical Intensive Care) 06/2023
1	Therapeutics 01/2022
1	Oral Administration 04/2011